Free On-Line Journals:

• Public Library of Science -- Biology A new, free e-journal with some outstanding content.
• European Molecular Biology Organization (EMBO) Journal Free on-line access to papers more than one year old.
• Genes and Development Journal  Free on-line access to papers more than one year old.
• Genetics  Free on-line access to papers more than three months old.
• Journal of Bacteriology  Free on-line access to papers more than six months old.
• Journal of Biological Chemistry  Free on-line access to papers from on-campus.
• Journal of Cell Biology  Free on-line access to papers more than six months old.
• Molecular Biology of the Cell Journal Free on-line access to papers more than two months old.
• Molecular and Cellular Biology Journal  Free on-line access to papers from on-campus.
• Nucleic Acids Research Journal  Free on-line access to papers more than one year old.
• Proceedings of the National Academy of Sciences, USA Free on-line access to papers more than six months old.

Journals which specialize in review articles:

• Current Opinion in Cell Biology
• Current Opinion in Genetics and Development
• Current Opinion in Immunology
• Current Opinion in Microbiology
• Trends in Biochemical Sciences
• Trends in Cell Biology
• Trends in Genetics
• Trends in Microbiology
• Trends in Molecular Medicine
• Minireviews from the Journal of Biological Chemistry
• Microbiology and Molecular Biology Reviews

Extra, Optional Readings on RNAi

• RNA Interference: Biology, Mechanism and Applications by Agrawal et al.
• MicroRNAs: Genomics, Biogenesis, Mechanism and Function by Bartel.
• Killing the messenger: short RNAs that silence gene expression by Dykxhoorn et al.
• RNAi: an ever-growing puzzle by Denli and Hannon
• The genetics of RNA silencing by Tijsterman et al.
  
• Nature Reviews Focus on RNAi
  

Extra, Optional Readings on Cellular Aging and Sir2

• In Methuselah's Mould by O'Neill
• Linking chromatin functions with metabolic networks: Sir2 family of NAD+-dependent deacetylastes by Denu
• Nicotinamide adenine dinucleotide, a metabolic regulator of transcription, longevity and disease by Lin and Guarente
  
• Enzymatic activities of Sir2 and chromatin silencing by Moazed
• Aging in Bacteria by Nystrom
  

Extra, Optional Readings on Cancer in Context

• The many faces of metalloproteases: cell growth, invasion, angiogenesis and metastasis by Chang and Werb
• The cell surface: the stage for matrix metalloproteinase regulation of migration by Seiki
• Regulation of TGF-ß signaling and its roles in progression of tumors by Miyazono et al.
• Smad-dependent and Smad-independent pathways in TGF-beta family signalling by Derynck and Zhang
• Results of Phase I Endostatin Trails.  by Eder et al.
  

Extra, Optional Readings on Rev and the RRE

• Synthesis and Processing of Viral RNA in Retroviruses by Coffin et al.
• HIV Rev protein regulates the transport of unspliced viral RNAs in Molecular Cell Biology by Lodish et al.
• The HIV-1 Rev protein by Pollard et al.
  

Useful Links:
Cre-lox system for making recombinant mice

NCBI  The National Center for Biotechnology Information is an outstanding site that collects a variety of important information and computer tools.

PubMed  The only way to search the scientific literature.  If you are confused, take a look at the PubMed Tutorial.

Nature Reviews Focus on RNAi  includes two useful animations

Expasy  One of the best sites for analyzing protein sequence.

The Protein Databank  For finding and viewing actual 3D protein structures.

Ergito  This site has a great section on Classic Experiments that is written by the people who actually did the experiments, along with some very useful images.  Free registration is required.

Free On-Line Textbooks from NCBI.  Fully searchable.  Especially useful texts include Molecular Cell Biology by Lodish et al.  Introduction to Genetic Analysis by Griffith et al. and Molecular Biology of the Cell by Alberts et al.

Interactive Biochemistry  Lots of interesting stuff here.  Great animations of Na+/K+ ATPase, electron transport and other things.  Wonderful reviews of a variety of current topics, such as HIV, "Mad Cow" Disease, and Cloning Mammals.  One of the better sites I've seen.

Online Mendelain Inheritance in Man  An amazing database of over 10,000 human genes and human diseases.  Lots of information, much of it easy-to-read, some of it is highly technical.  Lots of links to the primary scientific literature.

Committee on Publication Ethics

Office of Research Integrity at the National Institutes of Health

Guide for the Care and Use of Laboratory Animals

Declaration of Helsinki governing human research

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